Scientific Advisory Board
Mr. Steininger joined Acceleron in March 2007 as Senior Vice President, Manufacturing. He is responsible for managing the process development, analytical development, manufacturing, facility, and validation personnel that are involved in making clinical trial material in Acceleron’s disposable-based manufacturing facility.
He was previously the Vice President of Process Sciences at Millennium Pharmaceuticals. In this capacity, he was responsible for the processes for the bulk production of both large and small molecule clinical candidates and managed the development group which made Millennium’s first internally developed biologic using disposable bioreactors. Mr. Steininger also served as a VP within the Millennium Product and Portfolio Management organization.
Prior to joining Millennium, he held multiple roles at Genetics Institute (now Pfizer Pharmaceuticals) from 1984 to 2000, including Director of Clinical Production, Director of Process Technology, Director of Regulatory Affairs, and Senior Director of Research, Genomics. Mr. Steininger is a founding member of the Massachusetts Biomanufacturing Roundtable, and is a member of the advisory board for the Massachusetts chapter of ISPE, an Advisory Board member of the Chemical Engineering Department of the University of Massachusetts, Amherst, and on the Biotechnology Advisory Board for the RISTA program at the Cambridge High School. Mr. Steininger received a S.B. in chemistry from Massachusetts Institute of Technology and an M.S. in Chemical Engineering from the University of California, Berkeley.
Greg Zarbis-Papastoitsis, Ph.D. - Scientific Advisor
Dr Zarbis-Papastoitsis is currently the Senior Director of Protein Production and Analytical Development at Eleven Biotherapeutics. His group is responsible for producing novel recombinant proteins for in vitro and in vivo studies, and developing clinical enabling processes for transferring to CMO facilities.
With over 17 years of industrial experience, Greg has held a number of positions, including Senior Director of the Downstream Development and Analytical groups at Percivia and Associate Director of Process Development and Analytical Sciences at Syntonix (Biogen Idec Hemophilia), and Senior Scientist at Abbott and Millennium Pharmaceuticals. At Abbott he was one of the key scientists that lead the design of the second generation commercial process for Humira®.
While at PERCIVIA, Dr. Zarbis-Papastoitsis and his group published a number of publications on high capacity and single use technology purification processes for the industrial production of monoclonal antibodies. Greg also teaches a graduate course in downstream purification development at Northeastern University in Boston.
Greg received his PhD from the State University of New York at Binghamton.
Gaston de los Reyes - Scientific Advisor
Gastón is a co-founder of SPF Innovations LLC, a R&D venture developing new processes for the purification of biomolecules.
Gastón has over 35 years of experience developing, manufacturing and marketing products in high-value filtration and purification. He holds 16 patents in the field of separation and purification. He has managed R&D groups and has led product development and commercialization projects that have produced significant value to his previous employer (Millipore) and to SPF Innovations. He has experience in multiple industries: semi-conductor, biotech, biomedical and life science.
At SPF Innovations Gastón developed Single-Pass TFF – SPF™ Technology – in collaboration with his co-founder, Leon Mir. SPF Technology has been successfully commercialized in bioprocessing through a licensing agreement with Pall Corporation. SPF Innovations is continuing to develop the technology for laboratory and diagnostic applications.
Gastón has other commercial interests in the area of bioprocess simulation and in novel chromatographic processes for biopurification.
Gastón has a BS in Chemical Engineering from Georgia Tech and a MS in Mechanical Engineering from the University of Cincinnati. He has 2 children and 3 grandchildren, and speaks Spanish fluently. Gastón lives in the Boston area.
Dr. Andrew Zydney – Scientific Advisor
Dr. Andrew L. Zydney is currently Department Head and Walter L. Robb Family Endowed Chair in the Department of Chemical Engineering at The Pennsylvania State University. Professor Zydney received his Ph.D. in Chemical Engineering from M.I.T. in 1985 and he was a faculty member in the Chemical Engineering Department at the University of Delaware from 1985 - 2001. Professor Zydney's research is focused on membrane science and technology, with a particular emphasis on bioseparations and the purification of high value biological products. He has published more than 150 articles on these topics, including invited contributions to the Encyclopedia of Bioprocess Technology and the Handbook of Biomedical Engineering. Professor Zydney recently became Editor-in-Chief of the Journal of Membrane Science and he serves on the Editorial Boards for Separation and Purification Reviews, Separation Science and Technology and Biotechnology and Bioengineering. He served as President of the North American Membrane Society in 2002 - 2003, he was elected a fellow of the American Institute of Medical and Biological Engineers in 1998, he received the Excellence in Teaching Award from the University of Delaware in 1994 and he is a past recipient of the Distinguished Teacher Award (1999) and the Outstanding Young Faculty Award (1990) from the American Society of Engineering Education.
Business Advisory Board
Alan D. Lucas - Business Advisor
Alan has served in high level business development and marketing positions and consulted for start-up and emerging medical device companies. He has senior management experience enhancing investor value, including execution of successful IPOs and private placements. Alan has negotiated supplier agreements, distributor relationships, and marketing licensing agreements; and has directed market analysis, product specification, product launch, and sales management.
Meredith Fisher, PhD/MBA - Business Advisor
Enlight is a Boston-based venture creation company established in partnership with major pharmaceutical companies to develop breakthrough innovations that will fundamentally alter drug discovery and development. As Senior Director of Technology and Business Development at Enlight, Dr. Fisher focuses on technology sourcing and business development activities at Enlight. Prior to joining Enlight, Dr. Fisher completed her MBA at the MIT Sloan School of Management with a focus on entrepreneurship and technology strategy and her PhD at Harvard University in molecular microbiology. She has worked with a number of technology based start-up companies in business development and fundraising roles and spent several years in the biotech industry conducting drug discovery technology and assay development for Idenix Pharmaceuticals (formerly Novirio) and Anadys Pharmaceuticals (formerly Scriptgen). Dr. Fisher received her undergraduate degree from Mount Holyoke College.
David A. Fogel - Business Advisor
David Fogel is Managing Director of Swifton CFOs LLC, an outsourced CFO firm that provides emerging businesses with cost-effective and strategic financial leadership. David's expertise lies in constructing a reliable financial framework to attract funding, which is a valuable guide for his clients' continued growth.
As a contributor to the ongoing development of greater Boston's entrepreneurial ecosystem, he has been an active presenter and panelist with MassChallenge, CleanTech Open, WPI Venture Forum, Harvard Entrepreneurship Conference, 128 Innovation Capital Group, MIT Enterprise Forum Smart Start Program, Startup Leadership, The Capital Network and the MIT Entrepreneurial Teams (MIT e-Teams). He is also an active member of Mass TLC, MassMedic, Beacon Angels, TiE Angels and Mass Medical Angels.
David is Adjunct Instructor of Finance and Accounting in the Master’s program at the Tufts University Gordon Institute and in the MBA program at Worcester Polytechnic Institute. David is also a licensed Certified Public Accountant (CPA). David has a BS from Miami University (Ohio), and a MBA from the University of Cincinnati.
Vincent DeVito - Business Advisor
Mr. DeVito served as the U.S. Assistant Secretary of Energy for Policy and International Affairs. In that capacity, he was responsible for developing strategic policy while managing a multi-million dollar budget. He oversaw the Climate Change Technology Program, and maintains international government and industry contacts worldwide. Mr. DeVito is an authority on renewable energy development and corporate sustainability issues and has closely worked on legislative and regulatory corporate disclosure and compliance matters at the state, national, and international levels. He has strategically advised members of the President’s Cabinet, governors, ambassadors, and corporate leaders, and has participated in each major federal initiative that has impacted the energy industry this decade.